iPSC generation, culture and banking in 2019: what do I need to know to start my iPSC project today
Nuclear reprogramming and the discovery of the Nobel prize winning platform of iPSC generation has revolutionized the way we think about stem cells and their potential use in regenerative medicine. Today, more than a decade after the original discovery the techniques to generate, characterize and culture iPSC have been streamlined to make it almost a routine highly standardized process that can be recapitulated in most labs across the world. In this presentation I will summarize my laboratory current approaches to work with iPSC and I will provide a general overview of how the iPSC Core of the Center for Regenerative Medicine (CReM) at BU has generated one of the largest repositories of normal and disease-specific iPSC available to the entire scientific community.
Dr. Mostoslavsky received his MD from the University of Tucuman in Argentina and his PhD from the Hebrew University in Jerusalem, Israel. His longstanding interest in basic science and regenerative medicine brought him to Harvard Medical School to pursue postdoctoral studies with stem cells and gene therapy. In 2008 Dr. Mostoslavsky opened his own lab at Boston University. He is currently Associate Professor of Medicine in the Section of Gastroenterology in the Department of Medicine at Boston University School of Medicine. His main research interests are stem cells, disease modeling, regenerative medicine, gene correction and lentiviral vectors as tools for gene transfer. Dr. Mostoslavsky is a founder and Co-Director of the BU Center for Regenerative Medicine (CRe)