Organoids, spheroids, and 3D cell culture models, oh my!: Using advanced cell culture models, tissue clearing, and high content confocal microscopy to get the most of your in vitro studies
The rapid pace and growing expense of drug development is pushing pharmaceutical companies and researchers to improve the predictive capability of early-stage in vitro and animal model studies to improve the selectivity of the drug development funnel and to prevent late-stage failures. By improving both the predictive capability of in vitro models themselves and by extracting more complete data from cell culture models, the pace and efficacy of these studies can be improved. Through this webinar, Visikol will discuss the use of 3D cell culture models (e.g. organoids, spheroids, microtissues) for studying disease mechanisms, evaluating therapeutic efficacy, and assessing toxic liabilities. The use of tissue clearing and 3D imaging will be emphasized as a means for extracting quantitative insights into complex biological phenomenon.
Erin holds a bachelor’s degree from Brown University in Biomedical Engineering and a PhD from Georgia Tech in Bioengineering. With a background in topics ranging from immunoncology to cell mechanics, Erin has a passion for using advanced cell culture models to study complex disease mechanisms and evaluate new therapeutics. Erin brings over 8 years of in vitro assay development experience to Visikol as the Director of in Vitro Services, where she focuses on developing and executing assays to help biotech and pharmaceutical Clients study disease, evaluate therapeutics, and mitigate toxicity risks.